Functional Genomics Core

Functional Genomics Core Services

•Advice on the use of functional genomics for Targeted Therapeutics projects


 
•Target Discovery
 
      – TGI selection
 

               shRNA and siRNA libraries

              Genetic suppressor element (GSE) libraries

 
      – Transcriptomics
 

             Microarray hybridization 
             RNASeq

 
       – Identification of functional protein domains through GSE selection

 
•Target Validation
 
        – Target knockdown
 
     – Target overexpression
               
     – QPCR analysis of gene expression