Philip Hall, Pharm.D

Professor & MUSC Campus Dean

South Carolina College of Pharmacy

843.792.8250 :: Charleston

Pager :: 11942

hallpd@musc.edu

Philip Hall

About Dr. Hall

Dr. Philip D. Hall is the Campus Dean and Professor at the South Carolina College of Pharmacy, Medical University of South Carolina (MUSC) Campus.

Dean Hall received his bachelor's in pharmacy from the University of Georgia in 1986 then completed his Doctor of Pharmacy (Pharm.D.) from the Medical College of Virginia/Virginia Commonwealth University in 1988. With a special interest in oncology pharmacy, Hall completed an oncology pharmacy residency at the Audie L. Murphy Veterans Administration Hospital in San Antonio and cancer immunotherapy research fellowship at the University of Texas Health Science in San Antonio & University of Texas College of Pharmacy from 1988 - 1991. 

Dean Hall was recruited to the faculty of the MUSC College of Pharmacy in 1991 as an assistant professor. Serving in a number of leadership roles as a member of the faculty, both in the College and at the University level, he was promoted to associate professor in 1998 and was promoted to full professor in 2009. He served as associate dean for the MUSC campus from 2004 to 2010, taking a significant role in developing the joint curriculum of the integrated college, program assessment, and admitting and advising students.

He practiced pharmacy at the Hollings Cancer Center and Medical University Hospital in Charleston until February 2010, when he was asked to serve as interim campus dean at MUSC. He is board certified in both Pharmacotherapy and Oncology Pharmacy.

Education

Bachelor of Science, Pharmacy
University of Georgia, 1986

Doctor of Pharmacy
Medical College of Virginia, 1988

Research Interest

The overall goal of my research program is the clinical development of target peptide toxins for the treatment of cancer.  My major focus is investigating the development of an immune response to peptide toxins and its clinical impact.  Currently, we are developing a truncated diphtheria toxin (DT) linked to human GM-CSF for the treatment of acute myeloid leukemia.  Future studies include DT linked to interleukin-3 for the treatment of myeloid malignancies and the investigation of Anthrax and Pseudomonas toxins.

 

Selected Publications

  • Hall PD, Razzouk BI, Willoughby TE, McLean TW, Frankel AE.  The majority of children and   adolescents with acute myeloid leukemia have detectable anti- DT388GMCSF IgG concentrations but at concentrations that do not preclude in vivo activity.  J Ped Hematol Oncol 2002;24:521-6.
     
  • Frankel AE, Powell BL, Hall PD, Case LD, Kreitman RJ.  Phase I trial of a novel diphtheria toxin/GM-CSF protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.  Clin Cancer Res 2002;8:1004-1
     
  • Hall PD, Virella G, Willoughby T, Atchley DH, Kreitman RJ, Frankel AE.  Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia.  Clin Immunol 2001; 100(2):191-7.
     
  • Hotchkiss CE, Hall PD, Cline JM, Willingham MC, Kreitman RJ, Gardin J, Latimer A, Ramage J, Feely T, Frankel AE.  Toxicology and Pharmacokinetics of DTGM, a fusion toxin consisting of a truncated  cynomolgus monkeys.  Toxicol Appl Pharmacol 1999;158:152-60.
     
  • Hall PD, Willingham MC, Kreitman RJ, Frankel AE.  DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.  Leukemia 1999;13(4):629-33.

Research & Passion

His research, both clinical and laboratory-based, has focused on harnessing the immune system against cancer; he has received funding from the National Cancer Institute, Leukemia & Lymphoma Society, the American College of Clinical Pharmacy, and the pharmaceutical industry. Currently, his research focuses on factors that predict a student's success in pharmacy school.

One of his greatest passions is teaching and his teaching experience includes both didactic and experiential teaching. An acclaimed instructor, he has won a number of teaching awards both in the classroom and by the bedside. 

He has been named professor/teacher/preceptor of the year 10 times, including most recently as fourth-year class Professor of the Year and the Overall Teacher of the Year, both in 2009.

Hall lives in Mt. Pleasant, S.C. with his wife Rayna Kneuper-Hall, chief of Hematology/Oncology at the Ralph H. Johnson VA Medical Center and assistant professor of hematology/oncology at MUSC, and daughter Lauren and son Brandon.